Revolutionizing Cervical Cancer & STI Screening with HPV-STI Genomap Kit

Cervical cancer remains a pressing public health concern in India, with over 123,907 new cases and 77,348 fatalities annually (WHO 2023). Globally, more than 1 million STIs are acquired daily, with over 95% of cervical cancer cases attributed to HPV (Human Papillomavirus). Co-infections with HPV and other STIs amplify reproductive health risks and can speed up the progression to cervical cancer.

Challenges with Traditional HPV & STI Testing Methods

Conventional molecular tests-such as multiple PCRs-are limited by:

• Restricted multiplexing capabilities
• Incomplete genotyping information
• Prolonged turnaround and hands-on times
• Difficulty in detecting co-infections
• Increased risk of false positives from contamination

Why Choose NGS for HPV and STI Detection?

Next-Generation Sequencing (NGS) addresses these gaps with:

• High-throughput detection of multiple pathogens in one test
• Accurate genotyping for HPV and STI strains
• Simultaneous identification of co-infections
• Enhanced support for clinical decision-making

Introducing UNCODED’s HPV-STI Genomap Test Kit

The HPV-STI Genomap is a single-assay NGS-based test kit designed to detect and genotype a broad spectrum of HPV and STI pathogens.

Advanced NGS Test for Comprehensive HPV and STI Genotyping

• Utilizes amplicon-based multiplex PCR for enriched detection
• Targets 41 pathogens: 28 HPV types and 13 STI pathogens
• One-tube protocol ensures high-throughput efficiency
• Seamless integration with all Illumina platforms
• Unified workflow covering enrichment, sequencing, and reporting

Compatible with:

• iSeq 100
• MiniSeq™
• MiSeq™
• MiSeq i100 Series
• NextSeq™

Why UNCODED’s HPV-STI Kit Stands Out

UNCODED delivers a robust and scalable NGS-based STI genotyping kit designed for high accuracy and flexible application:

• Precise genotype-level results for HPV and STI targets
• Supports routine diagnostics, public health surveillance, and research use
• Detects co-infections with high specificity
• Tailored for cervical cancer screening and STI tracking in India and globally

Key Features of the HPV-STI Genomap Kit

• Target Enrichment Method: Multiplex PCR
• Total Pathogens Covered: 41 (28 HPV genotypes + 13 STI pathogens)
• DNA Input Required: ≥20 ng
• Benchwork Time: ~6 hours for 4×96-well plates
• Internal Control: Included
• Indexing Capacity: Up to 192 samples
• Platform Compatibility: All Illumina platforms (e.g., iSeq 100, MiniSeq™, MiSeq™, MiSeq i100 Series, NextSeq™)
• Read Length: 2 × 150 bp
• Data Analysis & Reporting: Simplified using proprietary software
• For Research Use Only

HPV Genotyping Panel

High-Risk & Probably High-Risk Types:

Associated with 99.7% of cervical cancer cases:

16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 (68a, 68b) 73, 26, 53, 82

Low-Risk Types:

Linked to benign conditions like genital warts:

6, 11, 40, 42, 43, 44, 55, 61, 81, 83

Why Choose UNCODED’s HPV-STI Genomap?

 

UNCODED’s HPV-STI Genomap is a powerful testing solution based on Next-Generation Sequencing (NGS). It helps labs detect and study HPV and other sexually transmitted infections (STIs) more accurately and efficiently.
This advanced platform is fast, scalable, affordable, and highly accurate—making it ideal for modern pathogen testing.

Designed for NGS-enabled laboratories, UNCODED simplifies the entire process—from identifying infections to analyzing and reporting results.
With just one test, labs can detect and identify different types of HPV and STIs, removing the need to run separate tests for each.

This all-in-one approach saves time, increases lab productivity, and delivers consistent, reliable results.

UNCODED provides high-quality data that can be used in routine diagnostics, lab monitoring, and large-scale health studies.
It helps healthcare professionals and public health teams make informed decisions quickly—whether responding to outbreaks, planning interventions, or monitoring disease trends.

Applications of HPV-STI Genomap: Promoting Excellence in Clinical, Research & Public Health

• Comprehensive Clinical Diagnostics: Detect and genotype multiple HPV and STI pathogens from a single clinical specimen—enabling better patient management and co-infection insights.
• Epidemiological Surveillance & Population Studies: Track pathogen prevalence, genotype shifts, and trends to support outbreak preparedness and public health policy.
• Translational and Precision Medicine Research: Conduct genotype-driven analysis on infection behavior, resistance mechanisms, and clinical outcomes to inform personalized medicine.
• Vaccine Evaluation & Longitudinal Monitoring: Assess infection persistence/clearance and vaccine efficacy by tracking genotype trends over time.
• Reference Lab & Quality Assurance: Serve as a reproducible, validated framework for assay benchmarking, lab accreditation, and multi-center research collaboration.
  

UNCODED’s advanced bioinformatics and automation tools significantly boost the speed and efficiency of both diagnostics and research workflows.
This enables faster discovery, better decision-making, and supports everything from individual patient diagnosis to high-level research studies.
That’s why UNCODED’s HPV-STI Genomap is a trusted solution for clinical, research, and public health laboratories worldwide