BRCA 1/2 Panel

Addressing the Global Burden of Breast Cancers

Breast and ovarian cancers continue to pose serious health challenges worldwide, impacting millions of women each year. As per World Health Organization data (2024), approximately 2.5 million new breast cancer cases and over 700,000 related deaths occur annually, while ovarian cancer accounts for an additional 310,000 new cases globally.

In India, the ICMR–NCRP (2025) reports nearly 232,832 breast cancer and 49,644 ovarian cancer cases each year. Breast cancer is the most frequently diagnosed cancer among Indian women, emphasizing the urgent need for enhanced awareness, early screening, and timely medical intervention.

Around 20–30% of hereditary cancer cases in India are associated with mutations in the BRCA1 and BRCA2 genes. Identifying these mutations early supports individualized risk evaluation, preventive care, and targeted therapeutic decisions—ultimately improving patient prognosis and survival outcomes.

Introducing the UNCODED BRCA12 Panel

Introducing the UNCODED BRCA1/2 Panel

The UNCODED BRCA1/2 Panel is a powerful NGS-based assay designed to deliver precise and actionable insights for hereditary cancer diagnostics and research. Utilizing advanced bioinformatics, it ensures accurate, consistent, and reproducible variant interpretation while addressing the limitations of traditional methods.

Why Choose UNCODED BRCA12 Panel

Why Choose UNCODED BRCA1/2 Panel

This high-performance NGS panel is tailored for comprehensive detection of clinically significant BRCA1 and BRCA2 mutations. Its optimized design and analytical workflow provide:

Actionable Insights: Supports clinicians in assessing risk, planning preventive strategies, and guiding personalized therapy.
Accurate Variant Detection: Confidently identifies pathogenic and clinically relevant BRCA mutations.
Scalable Workflow: Efficiently handles multiple samples, suitable for both research studies and clinical applications.
Clinical Utility: Facilitates genetic counselling and informed decision-making for patients and their families.

Next-Generation Sequencing (NGS) provides a high-throughput, comprehensive approach for analyzing genetic material. It allows simultaneous detection of multiple genetic variants, accelerates research, and delivers precise insights for diverse genomic applications.

 

Unlocking the Power of NGS in Genetic Analysis

Breast Cancer Applications

Applications

The UNCODED BRCA1/2 Panel equips clinicians and researchers with dependable detection of BRCA1 and BRCA2 variants, establishing it as a trusted solution for hereditary cancer risk assessment and precision oncology worldwide.

 

Clinical Genomics & Oncology

Evaluate cancer risk associated with BRCA1/2 mutations in: Breast (female and male), Ovarian, Prostate, Pancreatic, Melanoma, Fanconi Anaemia, Fallopian Tube, and Primary Peritoneal cancers. Assist clinicians in preventive care and treatment planning. Enable the effective use of PARP inhibitors in BRCA mutation–positive cancers. Support early detection and personalized therapies to improve patient outcomes. Facilitate familial risk assessment and provide data for genetic counselling.

Precision Medicine & Translational Research

Study BRCA-related DNA repair defects and associated molecular mechanisms. Track mutations and link variants to functional and translational research outcomes.

Pharmacogenomics

Analyze gene–drug interactions to predict treatment responses. Aid in the development of targeted therapies tailored to genetic profiles.

Population & Epidemiological Genomics

Investigate BRCA mutation frequency across diverse populations. Contribute to population-specific variant databases and public health research.

Reproductive & Genetic Counselling

Support carrier screening and familial risk evaluations. Provide comprehensive data for informed genetic counselling and preventive strategies.

Ordering Details
Cat. No. Kit Name Rxns
13911 BRCA1/2 Panel 8
13913 BRCA1/2 Panel 24
13915 BRCA1/2 Panel 96
Ordering Details of BRCA 1/2 Panel
Storage Condition

-20 °C to 4 °C

Frequently Asked Questions

Curious about workflow, accuracy, or compatibility? Find all your answers here

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Learn more about : BRCA 1/2 Panel

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BRCA1/2 Panel Brochure

Download these resources for detailed information on the UNCODED BRCA1/2 NGS Panel, including workflow, specifications, and applications.
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